A covalently bound photoisomerizable agonist. Comparison with reversibly bound agonists at electrophorus electroplaques

After disulphide bonds are reduced with dithiothreitol, trans-3- (α-bromomethyl)-3’-[α- (trimethylammonium)methyl]azobenzene (trans-QBr) alkylates a sulfhydryl group on receptors. The membrane conductance induced by this “tethered agonist” shares many properties with that induced by reversible agoni...

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Detalles Bibliográficos
Autores principales: Lester, HA, Krouse, ME, Nass, MM, Wassermann, NH, Erlanger, BF
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1980
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215740/
https://www.ncbi.nlm.nih.gov/pubmed/6246192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215740/
https://www.ncbi.nlm.nih.gov/pubmed/6246192

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