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NMR Structure and CD Titration with Metal Cations of Human Prion [Formula: see text] 2-Helix-Related Peptides

The 173–195 segment corresponding to the helix 2 of the C-globular prion protein domain could be one of several “spots” of intrinsic conformational flexibility. In fact, it possesses chameleon conformational behaviour and gathers several disease-associated point mutations. We have performed spectros...

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Detalles Bibliográficos
Autores principales: Ronga, Luisa, Palladino, Pasquale, Saviano, Gabriella, Tancredi, Teodorico, Benedetti, Ettore, Ragone, Raffaele, Rossi, Filomena
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2216051/
https://www.ncbi.nlm.nih.gov/pubmed/18274605
http://dx.doi.org/10.1155/2007/10720