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Sirt1 Deficiency Attenuates Spermatogenesis and Germ Cell Function

In mammals, Sirt1, a member of the sirtuin family of proteins, functions as a nicotinamide adenine dinucleotide-dependent protein deactylase, and has important physiological roles, including the regulation of glucose metabolism, cell survival, and mitochondrial respiration. The initial investigation...

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Detalles Bibliográficos
Autores principales: Coussens, Matthew, Maresh, John G., Yanagimachi, Ryuzo, Maeda, Gregg, Allsopp, Richard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2216432/
https://www.ncbi.nlm.nih.gov/pubmed/18270565
http://dx.doi.org/10.1371/journal.pone.0001571