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Sirt1 Deficiency Attenuates Spermatogenesis and Germ Cell Function
In mammals, Sirt1, a member of the sirtuin family of proteins, functions as a nicotinamide adenine dinucleotide-dependent protein deactylase, and has important physiological roles, including the regulation of glucose metabolism, cell survival, and mitochondrial respiration. The initial investigation...
Autores principales: | Coussens, Matthew, Maresh, John G., Yanagimachi, Ryuzo, Maeda, Gregg, Allsopp, Richard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2216432/ https://www.ncbi.nlm.nih.gov/pubmed/18270565 http://dx.doi.org/10.1371/journal.pone.0001571 |
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