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Inactivation and Secondary Structure in the D4/S4-5 Region of the SkM1 Sodium Channel

The D4/S4-5 interhelical region plays a role in sodium channel fast inactivation. Examination of S4-5 primary structure in all domains suggests a possible amphipathic helical conformation in which a conserved group of small hydrophobic residues occupies one contiguous surface with a more variable co...

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Detalles Bibliográficos
Autores principales: Filatov, Gregory N., Nguyen, Thao P., Kraner, Susan D., Barchi, Robert L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217155/
https://www.ncbi.nlm.nih.gov/pubmed/9607932