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Novel Gating Mechanism of Polyamine Block in the Strong Inward Rectifier K Channel Kir2.1

Inward rectifying K channels are essential for maintaining resting membrane potential and regulating excitability in many cell types. Previous studies have attributed the rectification properties of strong inward rectifiers such as Kir2.1 to voltage-dependent binding of intracellular polyamines or M...

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Detalles Bibliográficos
Autores principales: Lee, Jong-Kook, John, Scott A., Weiss, James N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217169/
https://www.ncbi.nlm.nih.gov/pubmed/10102936