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Cytoplasmic Unsaturated Free Fatty Acids Inhibit Atp-Dependent Gating of the G Protein–Gated K(+) Channel

This study reports the identification of an endogenous inhibitor of the G protein–gated (K(ACh)) channel and its effect on the K(ACh) channel kinetics. In the presence of acetylcholine in the pipette, K(ACh) channels in inside-out atrial patches were activated by applying GTP to the cytoplasmic side...

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Detalles Bibliográficos
Autores principales: Kim, Donghee, Pleumsamran, Apisate
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217204/
https://www.ncbi.nlm.nih.gov/pubmed/10694258