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Extracellular Mg(2+) Modulates Slow Gating Transitions and the Opening of Drosophila Ether-à-Go-Go Potassium Channels

We have characterized the effects of prepulse hyperpolarization and extracellular Mg(2+) on the ionic and gating currents of the Drosophila ether-à-go-go K(+) channel (eag). Hyperpolarizing prepulses significantly slowed channel opening elicited by a subsequent depolarization, revealing rate-limitin...

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Detalles Bibliográficos
Autores principales: Tang, Chih-Yung, Bezanilla, Francisco, Papazian, Diane M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217207/
https://www.ncbi.nlm.nih.gov/pubmed/10694260