Identification of a Peptide Toxin from Grammostola spatulata Spider Venom That Blocks Cation-Selective Stretch-Activated Channels

We have identified a 35 amino acid peptide toxin of the inhibitor cysteine knot family that blocks cationic stretch-activated ion channels. The toxin, denoted GsMTx-4, was isolated from the venom of the spider Grammostola spatulata and has <50% homology to other neuroactive peptides. It was isola...

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Detalles Bibliográficos
Autores principales: Suchyna, Thomas M., Johnson, Janice H., Hamer, Katherine, Leykam, Joseph F., Gage, Douglas A., Clemo, Henry F., Baumgarten, Clive M., Sachs, Frederick
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217226/
https://www.ncbi.nlm.nih.gov/pubmed/10779316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217226/
https://www.ncbi.nlm.nih.gov/pubmed/10779316

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