A Conducting State with Properties of a Slow Inactivated State in a Shaker K(+) Channel Mutant

In Shaker K(+) channel, the amino terminus deletion Δ6-46 removes fast inactivation (N-type) unmasking a slow inactivation process. In Shaker Δ6-46 (Sh-IR) background, two additional mutations (T449V-I470C) remove slow inactivation, producing a noninactivating channel. However, despite the fact that...

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Detalles Bibliográficos
Autores principales: Olcese, Riccardo, Sigg, Daniel, Latorre, Ramon, Bezanilla, Francisco, Stefani, Enrico
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217242/
https://www.ncbi.nlm.nih.gov/pubmed/11158167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217242/
https://www.ncbi.nlm.nih.gov/pubmed/11158167

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