Structural Similarities between Glutamate Receptor Channels and K(+) Channels Examined by Scanning Mutagenesis

The pores of glutamate receptors and K(+) channels share sequence homology, suggesting a conserved secondary structure. Scanning mutagenesis with substitution of alanine and tryptophan in GluR6 channels was performed based on the structure of KcsA. Our assay used disruption of voltage-dependent poly...

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Detalles Bibliográficos
Autores principales: Panchenko, Victor A., Glasser, Carla R., Mayer, Mark L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217257/
https://www.ncbi.nlm.nih.gov/pubmed/11279254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217257/
https://www.ncbi.nlm.nih.gov/pubmed/11279254

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