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Differential Regulation of ER Ca(2+) Uptake and Release Rates Accounts for Multiple Modes of Ca(2+)-induced Ca(2+) Release

The ER is a central element in Ca(2+) signaling, both as a modulator of cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) and as a locus of Ca(2+)-regulated events. During surface membrane depolarization in excitable cells, the ER may either accumulate or release net Ca(2+), but the conditions of stimu...

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Detalles Bibliográficos
Autores principales: Albrecht, Meredith A., Colegrove, Stephen L., Friel, David D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217286/
https://www.ncbi.nlm.nih.gov/pubmed/11865019
http://dx.doi.org/10.1085/jgp.20028484