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Differential Regulation of ER Ca(2+) Uptake and Release Rates Accounts for Multiple Modes of Ca(2+)-induced Ca(2+) Release
The ER is a central element in Ca(2+) signaling, both as a modulator of cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) and as a locus of Ca(2+)-regulated events. During surface membrane depolarization in excitable cells, the ER may either accumulate or release net Ca(2+), but the conditions of stimu...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217286/ https://www.ncbi.nlm.nih.gov/pubmed/11865019 http://dx.doi.org/10.1085/jgp.20028484 |