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Natural Bile Acids and Synthetic Analogues Modulate Large Conductance Ca(2+)-activated K(+) (BK(Ca)) Channel Activity in Smooth Muscle Cells
Bile acids have been reported to produce relaxation of smooth muscle both in vitro and in vivo. The cellular mechanisms underlying bile acid–induced relaxation are largely unknown. Here we demonstrate, using patch-clamp techniques, that natural bile acids and synthetic analogues reversibly increase...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217287/ https://www.ncbi.nlm.nih.gov/pubmed/11865021 http://dx.doi.org/10.1085/jgp.20028537 |