Natural Bile Acids and Synthetic Analogues Modulate Large Conductance Ca(2+)-activated K(+) (BK(Ca)) Channel Activity in Smooth Muscle Cells

Bile acids have been reported to produce relaxation of smooth muscle both in vitro and in vivo. The cellular mechanisms underlying bile acid–induced relaxation are largely unknown. Here we demonstrate, using patch-clamp techniques, that natural bile acids and synthetic analogues reversibly increase...

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Detalles Bibliográficos
Autores principales: Dopico, Alejandro M., Walsh, John V., Singer, Joshua J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217287/
https://www.ncbi.nlm.nih.gov/pubmed/11865021
http://dx.doi.org/10.1085/jgp.20028537

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