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TRPM7 Provides an Ion Channel Mechanism for Cellular Entry of Trace Metal Ions

Trace metal ions such as Zn(2+), Fe(2+), Cu(2+), Mn(2+), and Co(2+) are required cofactors for many essential cellular enzymes, yet little is known about the mechanisms through which they enter into cells. We have shown previously that the widely expressed ion channel TRPM7 (LTRPC7, ChaK1, TRP-PLIK)...

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Detalles Bibliográficos
Autores principales: Monteilh-Zoller, Mahealani K., Hermosura, Meredith C., Nadler, Monica J.S., Scharenberg, Andrew M., Penner, Reinhold, Fleig, Andrea
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217320/
https://www.ncbi.nlm.nih.gov/pubmed/12508053
http://dx.doi.org/10.1085/jgp.20028740