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Mg(2+)-dependent Gating and Strong Inward Rectification of the Cation Channel TRPV6

TRPV6 (CaT1/ECaC2), a highly Ca(2+)-selective member of the TRP superfamily of cation channels, becomes permeable to monovalent cations in the absence of extracellular divalent cations. The monovalent currents display characteristic voltage-dependent gating and almost absolute inward rectification....

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Detalles Bibliográficos
Autores principales: Voets, Thomas, Janssens, Annelies, Prenen, Jean, Droogmans, Guy, Nilius, Bernd
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217333/
https://www.ncbi.nlm.nih.gov/pubmed/12601087
http://dx.doi.org/10.1085/jgp.20028752