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Extracellular Ca(2+) Modulates the Effects of Protons on Gating and Conduction Properties of the T-type Ca(2+) Channel α(1G) (Ca(V)3.1)

Since Ca(2+) is a major competitor of protons for the modulation of high voltage–activated Ca(2+) channels, we have studied the modulation by extracellular Ca(2+) of the effects of proton on the T-type Ca(2+) channel α(1G) (Ca(V)3.1) expressed in HEK293 cells. At 2 mM extracellular Ca(2+) concentrat...

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Detalles Bibliográficos
Autores principales: Talavera, Karel, Janssens, Annelies, Klugbauer, Norbert, Droogmans, Guy, Nilius, Bernd
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217350/
https://www.ncbi.nlm.nih.gov/pubmed/12743167
http://dx.doi.org/10.1085/jgp.200308793