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Saxitoxin Is a Gating Modifier of hERG K(+) Channels

Potassium (K(+)) channels mediate numerous electrical events in excitable cells, including cellular membrane potential repolarization. The hERG K(+) channel plays an important role in myocardial repolarization, and inhibition of these K(+) channels is associated with long QT syndromes that can cause...

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Detalles Bibliográficos
Autores principales: Wang, Jixin, Salata, Joseph J., Bennett, Paul B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217357/
https://www.ncbi.nlm.nih.gov/pubmed/12771193
http://dx.doi.org/10.1085/jgp.200308812