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Saxitoxin Is a Gating Modifier of hERG K(+) Channels
Potassium (K(+)) channels mediate numerous electrical events in excitable cells, including cellular membrane potential repolarization. The hERG K(+) channel plays an important role in myocardial repolarization, and inhibition of these K(+) channels is associated with long QT syndromes that can cause...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217357/ https://www.ncbi.nlm.nih.gov/pubmed/12771193 http://dx.doi.org/10.1085/jgp.200308812 |