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Effect of Phosphatidylserine on Unitary Conductance and Ba(2+) Block of the BK Ca(2+)–activated K(+) Channel: Re-examination of the Surface Charge Hypothesis

Incorporation of BK Ca(2+)–activated K(+) channels into planar bilayers composed of negatively charged phospholipids such as phosphatidylserine (PS) or phosphatidylinositol (PI) results in a large enhancement of unitary conductance (g(ch)) in comparison to BK channels in bilayers formed from the neu...

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Detalles Bibliográficos
Autores principales: Park, Jin Bong, Kim, Hee Jeong, Ryu, Pan Dong, Moczydlowski, Edward
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217375/
https://www.ncbi.nlm.nih.gov/pubmed/12695485
http://dx.doi.org/10.1085/jgp.200208746