Regulated Exocytosis of GABA-containing Synaptic-like Microvesicles in Pancreatic β-cells

We have explored whether γ-aminobutyric acid (GABA) is released by regulated exocytosis of GABA-containing synaptic-like microvesicles (SLMVs) in insulin-releasing rat pancreatic β-cells. To this end, β-cells were engineered to express GABA(A)-receptor Cl(−)-channels at high density using adenoviral...

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Detalles Bibliográficos
Autores principales: Braun, Matthias, Wendt, Anna, Birnir, Bryndis, Broman, Jonas, Eliasson, Lena, Galvanovskis, Juris, Gromada, Jesper, Mulder, Hindrik, Rorsman, Patrik
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217446/
https://www.ncbi.nlm.nih.gov/pubmed/14769845
http://dx.doi.org/10.1085/jgp.200308966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217446/
https://www.ncbi.nlm.nih.gov/pubmed/14769845
http://dx.doi.org/10.1085/jgp.200308966

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