Differential Effects of Tyrosine Kinase Inhibitors on Volume-sensitive Chloride Current in Human Atrial Myocytes: Evidence for Dual Regulation by Src and EGFR Kinases

To determine whether protein tyrosine kinase (PTK) modulates volume-sensitive chloride current (I(Cl.vol)) in human atrial myocytes and to identify the PTKs involved, we studied the effects of broad-spectrum and selective PTK inhibitors and the protein tyrosine phosphatase (PTP) inhibitor orthovanad...

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Detalles Bibliográficos
Autores principales: Du, Xin-Ling, Gao, Zhan, Lau, Chu-Pak, Chiu, Shui-Wah, Tse, Hung-Fat, Baumgarten, Clive M., Li, Gui-Rong
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217456/
https://www.ncbi.nlm.nih.gov/pubmed/15024039
http://dx.doi.org/10.1085/jgp.200409013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217456/
https://www.ncbi.nlm.nih.gov/pubmed/15024039
http://dx.doi.org/10.1085/jgp.200409013

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