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Gating Dynamics of the Acetylcholine Receptor Extracellular Domain

We used single-channel recording and model-based kinetic analyses to quantify the effects of mutations in the extracellular domain (ECD) of the α-subunit of mouse muscle–type acetylcholine receptors (AChRs). The crystal structure of an acetylcholine binding protein (AChBP) suggests that the ECD is c...

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Detalles Bibliográficos
Autores principales: Chakrapani, Sudha, Bailey, Timothy D., Auerbach, Anthony
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217457/
https://www.ncbi.nlm.nih.gov/pubmed/15051806
http://dx.doi.org/10.1085/jgp.200309004