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Gating Dynamics of the Acetylcholine Receptor Extracellular Domain
We used single-channel recording and model-based kinetic analyses to quantify the effects of mutations in the extracellular domain (ECD) of the α-subunit of mouse muscle–type acetylcholine receptors (AChRs). The crystal structure of an acetylcholine binding protein (AChBP) suggests that the ECD is c...
Autores principales: | Chakrapani, Sudha, Bailey, Timothy D., Auerbach, Anthony |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217457/ https://www.ncbi.nlm.nih.gov/pubmed/15051806 http://dx.doi.org/10.1085/jgp.200309004 |
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