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Coupling of Voltage Sensing to Channel Opening Reflects Intrasubunit Interactions in Kv Channels
Voltage-gated K(+) channels play a central role in the modulation of excitability. In these channels, the voltage-dependent movement of the voltage sensor (primarily S4) is coupled to the (S6) gate that opens the permeation pathway. Because of the tetrameric structure, such coupling could occur with...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217479/ https://www.ncbi.nlm.nih.gov/pubmed/15623896 http://dx.doi.org/10.1085/jgp.200409194 |