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Coupling of Voltage Sensing to Channel Opening Reflects Intrasubunit Interactions in Kv Channels
Voltage-gated K(+) channels play a central role in the modulation of excitability. In these channels, the voltage-dependent movement of the voltage sensor (primarily S4) is coupled to the (S6) gate that opens the permeation pathway. Because of the tetrameric structure, such coupling could occur with...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217479/ https://www.ncbi.nlm.nih.gov/pubmed/15623896 http://dx.doi.org/10.1085/jgp.200409194 |