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Cysteine Modification Alters Voltage- and Ca(2+)-dependent Gating of Large Conductance (BK) Potassium Channels
The Ca(2+)-activated K(+) (BK) channel α-subunit contains many cysteine residues within its large COOH-terminal tail domain. To probe the function of this domain, we examined effects of cysteine-modifying reagents on channel gating. Application of MTSET, MTSES, or NEM to mSlo1 or hSlo1 channels chan...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217493/ https://www.ncbi.nlm.nih.gov/pubmed/15684095 http://dx.doi.org/10.1085/jgp.200409149 |