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Reversible Silencing of CFTR Chloride Channels by Glutathionylation

The cystic fibrosis transmembrane conductance regulator (CFTR) is a phosphorylation- and ATP-dependent chloride channel that modulates salt and water transport across lung and gut epithelia. The relationship between CFTR and oxidized forms of glutathione is of potential interest because reactive glu...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Oliva, Claudia, Li, Ge, Holmgren, Arne, Lillig, Christopher Horst, Kirk, Kevin L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217496/
https://www.ncbi.nlm.nih.gov/pubmed/15657297
http://dx.doi.org/10.1085/jgp.200409115