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Decreased Phosphatase Activity, Increased Ca(2+) Sensitivity, and Myosin Light Chain Phosphorylation in Urinary Bladder Smooth Muscle of Newborn Mice

Developmental changes in the regulation of smooth muscle contraction were examined in urinary bladder smooth muscle from mice. Maximal active stress was lower in newborn tissue compared with adult, and it was correlated with a lower content of actin and myosin. Sensitivity to extracellular Ca(2+) du...

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Detalles Bibliográficos
Autores principales: Ekman, Mari, Fagher, Katarina, Wede, Mia, Stakeberg, Karolina, Arner, Anders
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217499/
https://www.ncbi.nlm.nih.gov/pubmed/15684094
http://dx.doi.org/10.1085/jgp.200409212