Type-3 Ryanodine Receptors Mediate Hypoxia-, but Not Neurotransmitter-induced Calcium Release and Contraction in Pulmonary Artery Smooth Muscle Cells

In this study we examined the expression of RyR subtypes and the role of RyRs in neurotransmitter- and hypoxia-induced Ca(2+) release and contraction in pulmonary artery smooth muscle cells (PASMCs). Under perforated patch clamp conditions, maximal activation of RyRs with caffeine or inositol tripho...

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Detalles Bibliográficos
Autores principales: Zheng, Yun-Min, Wang, Qing-Song, Rathore, Rakesh, Zhang, Wan-Hui, Mazurkiewicz, Joseph E., Sorrentino, Vincenzo, Singer, Harold A., Kotlikoff, Michael I., Wang, Yong-Xiao
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217508/
https://www.ncbi.nlm.nih.gov/pubmed/15795312
http://dx.doi.org/10.1085/jgp.200409232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217508/
https://www.ncbi.nlm.nih.gov/pubmed/15795312
http://dx.doi.org/10.1085/jgp.200409232

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