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Enhanced transduction of colonic cell lines in vitro and the inflamed colon in mice by viral vectors, derived from adeno-associated virus serotype 2, using virus-microbead conjugates bearing lectin

BACKGROUND: Virus-mediated delivery of therapeutic transgenes to the inflamed colon holds a great potential to serve as an effective therapeutic strategy for inflammatory bowel disease, since local, long-term expression of the encoded therapeutic proteins in the colorectal system is potentially achi...

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Detalles Bibliográficos
Autores principales: Farlow, Samuel J, Jerusalmi, Alan, Sano, Takeshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217541/
https://www.ncbi.nlm.nih.gov/pubmed/18045466
http://dx.doi.org/10.1186/1472-6750-7-83