Barriers to antigenic escape by pathogens: trade-off between reproductive rate and antigenic mutability

BACKGROUND: A single measles vaccination provides lifelong protection. No antigenic variants that escape immunity have been observed. By contrast, influenza continually evolves new antigenic variants, and the vaccine has to be updated frequently with new strains. Both measles and influenza are RNA v...

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Detalles Bibliográficos
Autores principales: Frank, Steven A, Bush, Robin M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217548/
https://www.ncbi.nlm.nih.gov/pubmed/18005440
http://dx.doi.org/10.1186/1471-2148-7-229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217548/
https://www.ncbi.nlm.nih.gov/pubmed/18005440
http://dx.doi.org/10.1186/1471-2148-7-229

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