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Striatal Proteomic Analysis Suggests that First L-Dopa Dose Equates to Chronic Exposure
L-3,4-dihydroxypheylalanine (L-dopa)-induced dyskinesia represent a debilitating complication of therapy for Parkinson's disease (PD) that result from a progressive sensitization through repeated L-dopa exposures. The MPTP macaque model was used to study the proteome in dopamine-depleted striat...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217596/ https://www.ncbi.nlm.nih.gov/pubmed/18270577 http://dx.doi.org/10.1371/journal.pone.0001589 |