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Covalent activation of retinal rod cGMP-gated channels reveals a functional heterogeneity in the ligand binding sites

Ion channels gated by the binding of multiple ligands play a critical role in synaptic transmission and sensory transduction. It has been difficult to resolve the contribution of individual binding events to channel gating because ligands are continuously binding and unbinding at each site. In exami...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219270/
https://www.ncbi.nlm.nih.gov/pubmed/8833339