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Positive and Negative Coupling of the Metabotropic Glutamate Receptors to a G Protein–activated K(+) Channel, GIRK, in Xenopus Oocytes

Metabotropic glutamate receptors (mGluRs) control intracellular signaling cascades through activation of G proteins. The inwardly rectifying K(+) channel, GIRK, is activated by the βγ subunits of G(i) proteins and is widely expressed in the brain. We investigated whether an interaction between mGluR...

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Detalles Bibliográficos
Autores principales: Sharon, Dahlia, Vorobiov, Dmitry, Dascal, Nathan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219433/
https://www.ncbi.nlm.nih.gov/pubmed/9101406