Cargando…
Positive and Negative Coupling of the Metabotropic Glutamate Receptors to a G Protein–activated K(+) Channel, GIRK, in Xenopus Oocytes
Metabotropic glutamate receptors (mGluRs) control intracellular signaling cascades through activation of G proteins. The inwardly rectifying K(+) channel, GIRK, is activated by the βγ subunits of G(i) proteins and is widely expressed in the brain. We investigated whether an interaction between mGluR...
Autores principales: | Sharon, Dahlia, Vorobiov, Dmitry, Dascal, Nathan |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219433/ https://www.ncbi.nlm.nih.gov/pubmed/9101406 |
Ejemplares similares
-
Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturation
por: Rangel‐Garcia, Claudia I., et al.
Publicado: (2021) -
A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors
por: Berlin, Shai, et al.
Publicado: (2020) -
Mutual action by Gγ and Gβ for optimal activation of GIRK channels in a channel subunit-specific manner
por: Tabak, Galit, et al.
Publicado: (2019) -
Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase
por: Treiber, Fritz, et al.
Publicado: (2013) -
A novel small-molecule selective activator of homomeric GIRK4 channels
por: Cui, Meng, et al.
Publicado: (2022)