Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila

The lipid-modified morphogens Wnt and Hedgehog diffuse poorly in isolation yet can spread over long distances in vivo, predicting existence of two distinct forms of these mophogens. The first is poorly mobile and activates short-range target genes. The second is specifically packed for efficient spr...

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Detalles Bibliográficos
Autores principales: Katanaev, Vladimir L, Solis, Gonzalo P, Hausmann, George, Buestorf, Silke, Katanayeva, Natalya, Schrock, Yvonne, Stuermer, Claudia AO, Basler, Konrad
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219691/
https://www.ncbi.nlm.nih.gov/pubmed/18219274
http://dx.doi.org/10.1038/sj.emboj.7601981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219691/
https://www.ncbi.nlm.nih.gov/pubmed/18219274
http://dx.doi.org/10.1038/sj.emboj.7601981

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