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Prediction of enzyme function based on 3D templates of evolutionarily important amino acids

BACKGROUND: Structural genomics projects such as the Protein Structure Initiative (PSI) yield many new structures, but often these have no known molecular functions. One approach to recover this information is to use 3D templates – structure-function motifs that consist of a few functionally critica...

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Detalles Bibliográficos
Autores principales: Kristensen, David M, Ward, R Matthew, Lisewski, Andreas Martin, Erdin, Serkan, Chen, Brian Y, Fofanov, Viacheslav Y, Kimmel, Marek, Kavraki, Lydia E, Lichtarge, Olivier
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219985/
https://www.ncbi.nlm.nih.gov/pubmed/18190718
http://dx.doi.org/10.1186/1471-2105-9-17