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Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling

BACKGROUND: Cancer, like other diseases accompanied by strong metabolic disorders, shows characteristic effects on cell turnover rate, activity of modifying enzymes and DNA/RNA modifications, resulting also in elevated amounts of excreted modified nucleosides. For a better understanding of the impai...

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Detalles Bibliográficos
Autores principales: Bullinger, Dino, Neubauer, Hans, Fehm, Tanja, Laufer, Stefan, Gleiter, Christoph H, Kammerer, Bernd
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219991/
https://www.ncbi.nlm.nih.gov/pubmed/18047657
http://dx.doi.org/10.1186/1471-2091-8-25