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Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling
BACKGROUND: Cancer, like other diseases accompanied by strong metabolic disorders, shows characteristic effects on cell turnover rate, activity of modifying enzymes and DNA/RNA modifications, resulting also in elevated amounts of excreted modified nucleosides. For a better understanding of the impai...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219991/ https://www.ncbi.nlm.nih.gov/pubmed/18047657 http://dx.doi.org/10.1186/1471-2091-8-25 |