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Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF- [Formula: see text] B Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF- [Formula: see text] B Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages
In inflammation, bacterial products and proinflammatory cytokines induce the formation of large amounts of nitric oxide (NO) by inducible nitric oxide synthase (iNOS), and compounds that inhibit NO production have anti-inflammatory effects. In the present study, we systematically investigated the ef...
Autores principales: | Hämäläinen, Mari, Nieminen, Riina, Vuorela, Pia, Heinonen, Marina, Moilanen, Eeva |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2220047/ https://www.ncbi.nlm.nih.gov/pubmed/18274639 http://dx.doi.org/10.1155/2007/45673 |
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