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Methanethiosulfonate Derivatives Inhibit Current through the Ryanodine Receptor/Channel

To identify regions of the ryanodine receptor (RyR) important for ion conduction we modified the channel with sulfhydryl-reacting compounds. After addition of methanethiosulfonate (MTS) compounds channel conductance was decreased while other channel properties, including channel regulation by ATP, c...

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Detalles Bibliográficos
Autores principales: Quinn, Kerry E., Ehrlich, Barbara E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2220055/
https://www.ncbi.nlm.nih.gov/pubmed/9041453