Cargando…

Methanethiosulfonate Derivatives Inhibit Current through the Ryanodine Receptor/Channel

To identify regions of the ryanodine receptor (RyR) important for ion conduction we modified the channel with sulfhydryl-reacting compounds. After addition of methanethiosulfonate (MTS) compounds channel conductance was decreased while other channel properties, including channel regulation by ATP, c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quinn, Kerry E., Ehrlich, Barbara E.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2220055/ https://www.ncbi.nlm.nih.gov/pubmed/9041453

Ejemplares similares

Methanethiosulfonate derivatives as ligands of the STAT3-SH2 domain
por: Gabriele, Elena, et al.
Publicado: (2017)

Probing the Structure of the Diphtheria Toxin Channel : Reactivity in Planar Lipid Bilayer Membranes of Cysteine-substituted Mutant Channels with Methanethiosulfonate Derivatives
por: Huynh, Paul D., et al.
Publicado: (1997)

S-methyl Methanethiosulfonate: Promising Late Blight Inhibitor or Broad Range Toxin?
por: Joller, Charlotte, et al.
Publicado: (2020)

Surface charge potentiates conduction through the cardiac ryanodine receptor channel
Publicado: (1994)

Flux regulation of cardiac ryanodine receptor channels
por: Liu, Yiwei, et al.
Publicado: (2010)

Unitary Ca(2+) Current through Cardiac Ryanodine Receptor Channels under Quasi-Physiological Ionic Conditions
por: Mejía-Alvarez, Rafael, et al.
Publicado: (1999)

Ryanodine receptors
por: Capes, E Michelle, et al.
Publicado: (2011)

Suppressive Effects of S‐Methyl Methanethiosulfonate on Promotion Stage of Diethylnitrosamine‐initiated and Phenobarbital‐promoted Hepatocarcinogenesis Model
por: Sugie, Shigeyuki, et al.
Publicado: (1997)

The structural basis of ryanodine receptor ion channel function
por: Meissner, Gerhard
Publicado: (2017)

Modulation of Cardiac Ryanodine Receptor Channels by Alkaline Earth Cations
por: Diaz-Sylvester, Paula L., et al.
Publicado: (2011)

The N-Terminal Region of the Ryanodine Receptor Affects Channel Activation
por: Faltinova, Andrea, et al.
Publicado: (2017)

Coupling of SK channels, L-type Ca(2+) channels, and ryanodine receptors in cardiomyocytes
por: Zhang, Xiao-Dong, et al.
Publicado: (2018)

Hypernitrosylated ryanodine receptor/calcium release channels are leaky in dystrophic muscle
por: Bellinger, Andrew M., et al.
Publicado: (2009)

Interactions of a Reversible Ryanoid (21-Amino-9α-Hydroxy-Ryanodine) with Single Sheep Cardiac Ryanodine Receptor Channels
por: Tanna, Bhavna, et al.
Publicado: (1998)

Probing conformational changes during activation of ASIC1a by an optical tweezer and by methanethiosulfonate-based cross-linkers
por: Vaithia, Anand, et al.
Publicado: (2022)

Ryanodine Receptor Adaptation
por: Fill, M., et al.
Publicado: (2000)

Single-Particle Cryo-EM of the Ryanodine Receptor Channel in an Aqueous Environment
por: Baker, Mariah R., et al.
Publicado: (2015)

Unitary Ca(2+) Current through Mammalian Cardiac and Amphibian Skeletal Muscle Ryanodine Receptor Channels under Near-physiological Ionic Conditions
por: Kettlun, Claudia, et al.
Publicado: (2003)

mTOR signaling in mice with dysfunctional cardiac ryanodine receptor ion channel
por: Huang, Tai-Qin, et al.
Publicado: (2015)

Calcium Activation of Ryanodine Receptor Channels—Reconciling RyR Gating Models with Tetrameric Channel Structure
por: Zahradník, Ivan, et al.
Publicado: (2005)

Investigations of the Contribution of a Putative Glycine Hinge to Ryanodine Receptor Channel Gating
por: Euden, Joanne, et al.
Publicado: (2013)

Perspectives on Ryanodine Receptor Adaptation
Publicado: (2000)

Stabilization of the Skeletal Muscle Ryanodine Receptor Ion Channel-FKBP12 Complex by the 1,4-Benzothiazepine Derivative S107
por: Mei, Yingwu, et al.
Publicado: (2013)

Divalent cation conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum
Publicado: (1992)

Functional Impact of the Ryanodine Receptor on the Skeletal Muscle L-Type Ca(2+) Channel
por: Avila, Guillermo, et al.
Publicado: (2000)

Intermolecular Failure of L-type Ca(2+) Channel and Ryanodine Receptor Signaling in Hypertrophy
por: Xu, Ming, et al.
Publicado: (2007)

Ryanodine Receptors Selectively Interact with L Type Calcium Channels in Mouse Taste Cells
por: Rebello, Michelle R., et al.
Publicado: (2013)

Epac‐induced ryanodine receptor type 2 activation inhibits sodium currents in atrial and ventricular murine cardiomyocytes
por: Valli, Haseeb, et al.
Publicado: (2017)

Structure of a mammalian ryanodine receptor
por: Zalk, Ran, et al.
Publicado: (2014)

Arrhythmogenic mechanisms in ryanodine receptor channelopathies
por: ZHAO, Yan-Ting, et al.
Publicado: (2014)

Two Regions of the Ryanodine Receptor Calcium Channel Are Involved in Ca(2+)-Dependent Inactivation
por: Gomez, Angela C., et al.
Publicado: (2014)

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling
por: Dulhunty, Angela F., et al.
Publicado: (2018)

Dampened activity of ryanodine receptor channels in mutant skeletal muscle lacking TRIC‐A
por: El‐Ajouz, Sam, et al.
Publicado: (2017)

A model for ionic conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum
Publicado: (1992)

The ryanodine receptor/junctional channel complex is regulated by growth factors in a myogenic cell line
Publicado: (1991)

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues
Publicado: (1995)

Purified ryanodine receptor from rabbit skeletal muscle is the calcium- release channel of sarcoplasmic reticulum
Publicado: (1988)

Questions about Adaptation in Ryanodine Receptors
por: Lamb, G.D., et al.
Publicado: (2000)

Structural Insight Into Ryanodine Receptor Channelopathies
por: Hadiatullah, Hadiatullah, et al.
Publicado: (2022)

Inhibition of CaMKII Does Not Attenuate Cardiac Hypertrophy in Mice with Dysfunctional Ryanodine Receptor
por: Chakraborty, Asima, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_h4p3kplnf2h9jff7dtckoei85v