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N-acetylcysteine prevents HIV gp 120-related damage of human cultured astrocytes: correlation with glutamine synthase dysfunction

BACKGROUND: HIV envelope gp 120 glycoprotein is released during active HIV infection of brain macrophages thereby generating inflammation and oxidative stress which contribute to the development of the AIDS-Dementia Complex (ADC). Gp120 has also been found capable to generate excitotoxic effect on b...

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Detalles Bibliográficos
Autores principales: Visalli, Valeria, Muscoli, Carolina, Sacco, Iolanda, Sculco, Francesca, Palma, Ernesto, Costa, Nicola, Colica, Carmela, Rotiroti, Domenicantonio, Mollace, Vincenzo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2221944/
https://www.ncbi.nlm.nih.gov/pubmed/18062818
http://dx.doi.org/10.1186/1471-2202-8-106