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Crystallization and preliminary X-ray diffraction analysis of Nsp15 from SARS coronavirus

The non-structural protein Nsp15 from the aetiological agent of SARS (severe acute respiratory syndrome) has recently been characterized as a uridine-specific endoribonuclease. This enzyme plays an essential role in viral replication and transcription since a mutation in the related H229E human coro...

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Detalles Bibliográficos
Autores principales: Ricagno, Stéfano, Coutard, Bruno, Grisel, Sacha, Brémond, Nicolas, Dalle, Karen, Tocque, Fabienne, Campanacci, Valérie, Lichière, Julie, Lantez, Violaine, Debarnot, Claire, Cambillau, Christian, Canard, Bruno, Egloff, Marie-Pierre
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222560/
https://www.ncbi.nlm.nih.gov/pubmed/16582498
http://dx.doi.org/10.1107/S1744309106009407