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A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition
Mechanical hyperalgesia is a clinically-relevant form of pain sensitization that develops through largely unknown mechanisms. TRPA1, a Transient Receptor Potential ion channel, is a sensor of pungent chemicals that may play a role in acute noxious mechanosensation and cold thermosensation. We have d...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222610/ https://www.ncbi.nlm.nih.gov/pubmed/18086313 http://dx.doi.org/10.1186/1744-8069-3-40 |