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The oncoprotein H-Ras(V12 )increases mitochondrial metabolism

BACKGROUND: Neoplastic cells increase glycolysis in order to produce anabolic precursors and energy within the hypoxic environment of a tumor. Ras signaling is activated in several cancers and has been found to regulate metabolism by enhancing glycolytic flux to lactate. We examined the effects of s...

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Detalles Bibliográficos
Autores principales: Telang, Sucheta, Lane, Andrew N, Nelson, Kristin K, Arumugam, Sengodagounder, Chesney, Jason
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222650/
https://www.ncbi.nlm.nih.gov/pubmed/18053146
http://dx.doi.org/10.1186/1476-4598-6-77