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The oncoprotein H-Ras(V12 )increases mitochondrial metabolism
BACKGROUND: Neoplastic cells increase glycolysis in order to produce anabolic precursors and energy within the hypoxic environment of a tumor. Ras signaling is activated in several cancers and has been found to regulate metabolism by enhancing glycolytic flux to lactate. We examined the effects of s...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222650/ https://www.ncbi.nlm.nih.gov/pubmed/18053146 http://dx.doi.org/10.1186/1476-4598-6-77 |