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Single TNFα trimers mediating NF-κB activation: stochastic robustness of NF-κB signaling
BACKGROUND: The NF-κB regulatory network controls innate immune response by transducing variety of pathogen-derived and cytokine stimuli into well defined single-cell gene regulatory events. RESULTS: We analyze the network by means of the model combining a deterministic description for molecular spe...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222661/ https://www.ncbi.nlm.nih.gov/pubmed/17925009 http://dx.doi.org/10.1186/1471-2105-8-376 |