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Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity

BACKGROUND: Retroviruses selectively encapsidate two copies of their genomic RNA, the Gag protein binding a specific RNA motif in the 5' UTR of the genome. In human immunodeficiency virus type 2 (HIV-2), the principal packaging signal (Psi) is upstream of the major splice donor and hence is pre...

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Detalles Bibliográficos
Autores principales: L'Hernault, Anne, Greatorex, Jane S, Crowther, R Anthony, Lever, Andrew ML
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222663/
https://www.ncbi.nlm.nih.gov/pubmed/18078509
http://dx.doi.org/10.1186/1742-4690-4-90