Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours.

In a series of 46 glioblastomas, 16 anaplastic astrocytomas and eight astrocytomas, all tumours retaining one or both alleles of CDKN2A (48 tumours) and CDKN2B (49 tumours) were subjected to sequence analysis (entire coding region and splice acceptor and donor sites). One glioblastoma with hemizygou...

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Detalles Bibliográficos
Autores principales: Schmidt, E. E., Ichimura, K., Messerle, K. R., Goike, H. M., Collins, V. P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222701/
https://www.ncbi.nlm.nih.gov/pubmed/9000591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222701/
https://www.ncbi.nlm.nih.gov/pubmed/9000591

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